A division of the Department of Biomedical Informatics and Medical Education  |  UW Medicine
Biomedical and Health Informatics

Faculty Profiles - All Faculty

Barry Aaronson MD, FACP, SFHM
Hospitalist & Associate Medical Director for Clinical Informatics
- Virginia Mason Medical Center, Seattle
Clinical Associate Professor Department of Medicine
Clinical Associate Professor Dept. of Biomedical Informatics & Medical Education
- University of Washington, Seattle

Background: Working 1/2 time as a Hospitalist at Virginia Mason Medical Center and 1/2 time as the Associate Medical Director for Clinical Informatics at Virginia Mason. Completed in 2009 National Library of Medicine Post-Doctoral Fellowship within BHI. During fellowship completed a clinical trial of an EHR based tool to assist the UWMC and HMC Rapid Response Teams proactively identify deteriorating patients outside the intensive care units in an effort to reduce mortality, unexpected cardiac arrest and unexpected transfers to the intensive care units.

Current Research:  Currently leading clinical trial of a tool we deployed within the EHR called the "Quality Safety Dashboard." This dashboard is a real-time feedback system for hospital core measure compliance that is displayed on large wall mounted monitors to aid in situational awareness by all members of the care team in an effort to achieve 100% compliance with core measures.

Representative Publications:

  • Solti I, Aaronson BA, Fletcher G, Solti M, Gennari J, Cooper M, Payne T, “Building an Automated Problem List Based on Natural Language Processing: Lessons Learned in the Early Phase of Development” AMIA Annu Symp Proc. 2008; 2008: 687
  • Hanson D, Aaronson B, Krevat S. An EHR Structured Discharge Documentation Tool to Mistake Proof CHF Bundle Compliance. (2010), Innovations Poster Abstract. Journal of Hospital Medicine, 5: 84–110. doi: 10.1002/jhm.708
  •  White A, Aaronson B, Fletcher G. et. al. Initial Pilot of an Electronic Health Record Dashboard to Improve Compliance with Inpatient Quality Measures. (2010), Innovations Poster Abstract. Journal of Hospital Medicine, 5: 84–110. doi: 10.1002/jhm.708
  • Aaronson BA, Westley M, Spohnholtz M, Tyler L, Dunning, E. Evaluation of an Electronic Early Warning System for the Detection of Critically Ill Hospital Patients. (2008), Innovations Abstracts. Journal of Hospital Medicine, 3: 49–74. doi: 10.1002/jhm.330
  •  Aaronson B, Stone D, Schaft M, et. al. An Electronic Health Record Based Tool to Aid in the Prevention of Avoidable Deaths in Hospital Patients. (2009), Innovations Poster Abstracts. Journal of Hospital Medicine, 4: 73–92. doi: 10.1002/jhm.546

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Neil Abernethy, PhD
Assistant Professor, Biomedical Informatics and Medical Education
Joint Assistant Professor, Health Services, School of Public Health

Background:  B.S. Biochemistry (NCSU); B.S. Applied Mathematics (NCSU); Ph.D. Biomedical Informatics (Stanford University). Scientific programming focused on molecular evolution, knowledge representation for bioinformatics (bio-ontologies), and genetic networks (Ingenuity Systems). Graduate training involving molecular evolution, epidemiology, social network models of infectious disease, and interactive data visualization to integrate complex public health information. Post-graduate research in epidemiology and biostatistics.

Research:  Models of infectious disease (including TB, HIV, and influenza), molecular epidemiology, network analysis, disease surveillance, data information, systems biology, data standards and integration, with a focus on infectious diseases and global health.

Other interests: Environmental interventions for infectious disease, high-throughput biology, evolutionary processes, bibliometrics, sensor technology, user interfaces, and game theory.

Representative Publications:

  • Aga RS, Fair E, Abernethy NF, DeRiemer K, Paz E, Kawamura L, Small PM, Kato-Maeda J. Microevaluation of the Direct Repeat Locus on Mycobacterium tuberculosis in a Strain Prevalent in San Francisco. Journal of Clinical Mircobiology 2006;April 44(4):1558-1560.
  • Jeffries D, Abernethy NF, De Jong BC. Supervised learning for the automated transcription of spacer classification from spoligotype films. Medical Research Council (UK), The Gambia. BMC Informatics 2009 August;10:248.
  • Hills RA, Reeder B, Revere D, Lober W, Abernethy NF. Immunization Information and Population Data Sources: The Information Needs of Public Health Practitioners. ACM International Health Informatics 2010.
  • Guidry A, Walson J, Abernethy NF. Linking information systems for HIV care and research in Kenya. ACM International Health Informatics 2010.
  • Abernethy NF, Dereimer K, Small PM: A National Survey of Data Standards in Contact Investigation Forms for Tuberculosis. Proceedings of the American Medical Informatics Association (AMIA) 2011 (in press).

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Nick Anderson, MS, PhD
Assistant Professor, Biomedical Informatics and Medical Education
Adjunct Assistant Professor, Bioethics and Humanities
Associate Director, Biomedical Informatics Core, Institute of Translational Health Sciences

Background:  10 years in health software industry. BS in Computer Science (Evergreen State College 1993), MS in Biomedical Informatics (Oregon Health Science University 2004), Ph.D. in Biomedical Informatics (University of Washington 2007). Research on social and technical issues involving designing, developing, implementing and extending clinical/translational research systems. Example research areas are: user needs evaluation as to support usability in rich data information systems, policy associated with biological data banks, bioinformatics workflows, personal health information management, decision analysis, cross-institutional clinical data sharing.

Representative Publications: 

  • Anderson, N, Edwards, K, Building a Chain of Trust: Using policy and practice to enhance trustworthy data discovery and sharing, Association of Computing Machinery Workshop on Workshop on Governance of Technology, Information, and Policies, Austin TX, Dec 2010
  • Anderson, N, Abend, A, Mandel, A, Geraghty, E, Gabriel, D, Wynden, R, Kamerick, M, Anderson, K, Rainwater, J, Tarczy-Hornoch, P Implementation of a De-identified Federated Data Network for Population-based Cohort Discovery, JAMIA 2011 (in press)
  • Chilana PK, Fishman E, Geraghty E, Tarczy-Hornoch P, Wolf F, Anderson NR. “Characterizing Data Discovery and End-user Computing Needs in Clinical Translational Science”. Journal of Organization and End User Computing (JOEUC) Feb, 2010
  • Fullerton, S. M. Anderson, N. R. , Guzauskas, G., Freeman, D. Fryer-Edwards, K. Meeting the governance challenges of next generation biorepository research.Sci. Transl. Med. 3, 14cm3 (2010).
  • Anderson NR, Lee ES, Brockenbrough JS, Minie ME, Fuller S, Brinkley J, Tarczy-Hornoch P. An Assessment of the Data Management Needs of Academic Biomedical Researchers. Journal of the American Informatics Association, 14(4):478-488, 2007

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James Brinkley, MD, PhD
Professor, Biological Structure
Joint Professor, Biomedical Informatics and Medical Education
Adjunct Professor, Computer Science and Engineering
Fellow, American College of Medical Informatics
Director, UW Structural Informatics Group
Associate Director, Biomedical Informatics Core, Institute of Translational Health Science (ITHS)

Background: Informatics research on 2-D and 3-D imaging and modeling, ontologies, data management, data integration and visualization; established in 1991 the subfield of biomedical informatics known as "structural informatics," whose fundamental premise is that the structure of the body is the most rational means for organizing biomedical information.

Education: M.D., University of Washington; Ph.D., Stanford University, Medical Computer Engineering.

Current primary interests: structural informatics with emphasis on multimedia data management, ontologies, data integration, and visualization as applied to translational medicine; practical data management and integration as a service.

Current major project that could use student help:  the Foundational Model of Anatomy (FMA), a large ontology of anatomy; semantic web based approaches for creating views and web-service access to large ontologies like the FMA; image annotation using semantic-web methods; ontology-based data management and integration; ontology-based visualization of 3-D anatomical scenes in virtual worlds for education and as a substrate for visualization of biomedical information.  Application areas depend on funding; currently include craniofacial development and malformation, brain mapping, proteomics, distributed anatomy education in virtual worlds, low cost/open source management and integration of clinical/translational data and knowledge.

For more information see http://sig.biostr.washington.edu (this page is currently out of date, so please contact me through email for updates).

Representative Publications: 

  • Brinkley, J.F. 1991  Structural informatics and its applications in medicine and biology. Academic Medicine 66(10):589-591.
  • Rosse, C., Shapiro, L.G. and Brinkley, J.F. 1998 The Digital Anatomist foundational model: principles for defining and structuring its concept domain. Journal of the American Medical Informatics Association, Symposium Supplement, pp 820-824.
  • Detwiler LT, Suciu D, Franklin JD, Moore EB, Poliakov AV, Lee ES, Corina D, Ojemann GA, Brinkley JF. Distributed XQuery-based integration and visualization of multimodality data: Application to brain mapping. Frontiers in Neuroinformatics (2009) 3:2. doi:10.3389/neuro.11.002.2009. http://sigpubs.biostr.washington.edu/archive/00000234/.
  • Shaw MS, Detwiler LT, Noy NF, Brinkley JF, Suciu D. vSPARQL: A view definition language for the semantic web. Journal of Biomedical Informatics. 44(1):102-117. 2010 

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Jan Carline, PhD
Professor, Biomedical Informatics and Medical Education

Background: 30 yrs experience in support of medical education and its evaluation.

Research: a) evaluation of curricular innovations, b) use of program evaluation to improve education

Representative Publications:

  • Carline JD, Curtis JR, Wenrich MD, Shannon SE, Ambrozy DM, Ramsey PG.  Physicians’ interactions with health care teams and systems in the care of dying patients: Perspectives of dying patients, family members, and health care professionals.  Journal of pain and symptom management, 25:19-28, 2003.
  • Carline JD, Patterson DG.  Assessing Health Profession Partnerships: Characteristics of professions schools, public school systems and community-based organizations in successful partnerships.  Academic Medicine, 78(5): 467-482, 2003.
  • Carline JD: Funding medical education research: Opportunities and issues. Academic Medicine 79(10): 918-924, 2004.
  • Carline JD, O’Sullivan PS, Gruppen LD, Richardson-Nassif K. Crafting successful relationships with the IRB. Academic Medicine 82:10: S57-60, 2007.
  • Shi-Hao Wen, Jing-Song Xu, Carline JD, Fei Zhong, Yi-Jun Zhong, Sheng-Juan Shen. Wei-Min Ren, Li Qu, Yue Wang, Guo-En Fang. Effects of teaching evaluation: a case study. International Journal of Medical Education http://www.ijme.net/archive/2/teaching-evaluation-effects/
  • Amies AM, Dobie S, Smith S, Tamura GS, Carline JD.  Where do medical students turn? The role of the assigned mentor in the fabric of support. Teaching and Learning in Medicine 23(3); 105-111, 2011.

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David Chou, MD
Professor, Laboratory Medicine
Adjunct Associate Professor, Biomedical Informatics and Medical Education

Background: 30+ years computer science, laboratory medicine, informatics. Dr. Chou is also the director, Informatics and Phlebotomy, UW and Harborview Medical Centers and is the Chief Technical Officer for Information Technology Services, UW Medicine

Funded research: co-PI of informatics research grants on a) the application of emerging technologies to clinical decision support and clinical biorepositories, b) intersection of laboratory information systems, clinical information systems, clinical lab automation.

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Daniel Cook, MD, PhD
Background:  Dr. Cook has been developing tools for the representation and analysis of complex dynamic systems for 40 years. He earned a BSME in mechanical engineering from the University of Michigan and spent 4 years as a Boeing while earning his Masters degree in Mechanical Engineering from the UW. To follow-up his masters thesis project on the simulation of glucose-induced insulin secretion, he entered the UW's Medical Scientist Training Program to earn his MD and a PhD in Physiology & Biophysics. After making seminal discoveries in the electrophysiology of insulin secretion,

Dr. Cook returned to his interests in the computational representation and analysis of complex systems. He authored two graphics-based applications for diagramming and analyzing cell networks and based one program, Chalkboard, on a linguistic metaphor of entity interactions using noun/verb constructs. He then connected with Dr. Cornelius Rosse and the FMA project to learn state-of-the-art knowledge representation and query methods as part of the DARPA-sponsored Virtual Soldier Project.

In subsequent collaborations with Drs. John Gennari, James Brinkley, and others, he is developing informatics methods for the declarative representation of physics-based biosimulation models as needed by, for example, the European Virtual Physiological Human and IUPS Physiome projects. The major contributions to this effort are an ontology of classical physics, the Ontology of Physics for Biology (OPB), and light-weight OWL representations (SemSim models) that map the biological and mathematical content of individual simulation models to the FMA and OPB.

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Walter H. Curioso, MD, MPH, PhDc
Research Professor, Universidad Peruana Cayetano Heredia, Peru.
Affiliate Assistant Professor, Biomedical Informatics and Medical Education, University of Washington.

Education: MD (Universidad Peruana Cayetano Heredia); Master's in Public Health (University of Washington); Certificate in Biomedical and Health Informatics (University of Washington); Ph.D. candidate in Biomedical and Health Informatics, University of Washington.

Current research:  His latest projects involve using mobiles devices to support adherence among HIV and diabetic patients, using cell phones to support prenatal care among pregnant women, and using cell phones and the Internet to develop a real-time surveillance system for adverse events. Other past research descriptions available at home page. International consultant on eHealth, mHealth, and telemedicine.
Editorial board: PLoS ONE, Revista Peruana de Medicina Experimental y Salud Pública

Representative Publications:

  • Curioso WH, Fuller S, Garcia PJ, Holmes KK, Kimball AM. Ten Years of International Collaboration in Biomedical Informatics and Beyond: The AMAUTA Program in Peru. J Am Med Inform Assoc 2010;17(4):477-480. (PubMed / MEDLINE). 
  • Curioso WH, Quistberg DA, Cabello R, Gozzer E, Garcia PJ, Holmes KK, Kurth AE. "It´s time for your life": How should we remind patients to take medicines using short text messages? AMIA Annu Symp Proc 2009;:129-133. (PubMed / MEDLINE).
  • Curioso WH, Peinado J, Rubio CF, Lazo-Escalante M, Castagnetto JM. Biomedical and Health Informatics in Peru: Significance for Public Health. Health Info Libr J. 2009;26(3): 246-251. (PubMed / MEDLINE).  
  • Curioso WH, Kurth AE. Access, use and perceptions regarding Internet, cell phones and PDAs as a means for health promotion for people living with HIV in Peru. BMC Medical Informatics and Decision Making 2007; 7:24. (PubMed / MEDLINE). 
  • Curioso WH, Karras BT, Campos PE, Buendia C, Holmes KK, Kimball AM. Design and Implementation of Cell PREVEN: A Real-Time Surveillance System for Adverse Events Using Cell Phones in Peru. AMIA Annu Symp Proc 2005; 176-180. (PubMed / MEDLINE).  

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Twitter: @waltercurioso
Website

Valerie Daggett, PhD
Professor, Bioengineering
Adjunct Professor, Biochemistry
Adjunct Professor, Biomedical Informatics and Medical Education
B.A. Reed College, PhD UCSF, Postdoctoral Fellow, Stanford University

Background: 25 yrs molecular modeling proteins/peptides. Dr. Daggett is on the editorial boards: Biochemistry, Structure, and Biomedical Computation Review (BCR). Senior Editor: Protein Engineering, Design, and Selection. Founding member of the Biomolecular Structure and Design Program. Editor of a 2003 volume on Protein Simulations for Advances in Protein Chemistry. Member of NIH Macromolecular Structure and Function B Study Section, July 2005 - 2008. Biophysical Society Fellow, 2011. Funded Research: a) Molecular dynamics simulations of protein unfolding (NIH)| b)  Characterization of prion protein conformational changes (NIH)| c)  Design and characterization of alpha-sheet compounds (NSF)| c) Data exploration and visualization (Microsoft)| and d) Molecular Dynameomics (DOE).

Representative Publications:

  • Van der Kamp M.W., Schaeffer R.D., Jonsson A.L., Scouras A.D., Simms A.M., Toofanny R.D., Benson N.C., Anderson P.C., Merkley E.D., Rysavy S., Bromley D., Beck D.A.C., and Daggett V. Dynameomics: A Comprehensive Database of Protein Dynamics. Structure 18:423-435, 2010.
  • Schaeffer R.D, Jonsson A.L., Simms A.M., and Daggett V. Generation of a Consensus Protein Domain Dictionary. Bioinformatics 27:46-54, 2011. 
  • Toofanny, R.D., Simms, A.M., Beck, D.A.C. and V. Daggett, Implementation of 3D spatial indexing and compression in a large-scale molecular dynamics simulation database for rapid atomic contact detection, BMC Bioinformatics, in press, 2011.
  • Benson, N.C. and V. Daggett, Wavelet Analysis of Protein Motion, J. Wavelets, Multiresol. Info. Processing, in press, 2011.
  • Simms, A.M. and V. Daggett, Protein simulation data in the relational model, J. of Supercomp., in press, 2011

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Mark Del Beccaro, MD, FAAP
Professor, Vice Chair for Clinical Affairs, Department of Pediatrics,
Adjunct Professor, Department of Biomedical Informatics and Medical Education
University of Washington School of Medicine
Pediatrician in Chief, Seattle Children's Hospital
Attending Physician, Emergency Department, Seattle Children’s Hospital

Background:  Undergraduate education (BS in Biologic Sciences) at Stanford University, MD degree from the University of Washington (Seattle).   Completed both a Pediatric residency and was the Chief Resident in Pediatrics at the University of Washington and Seattle Children’s Hospital.  Was the CMIO at Seattle Children’s and has over 15 years experience in clinical systems selection, design, and implementation.   Involved in numerous national Health IT groups including HL-7, past co-chair of CCHIT Inpatient group, and is current Chair of the American Academy of Pediatrics Council on Clinical Information Technology (COCIT) Executive Committee.

Research Interests:  Clinical decision support, using clinical databases to measure and improve health care outcomes and resource utilization.  Currently on the Exec Committee for a consortium of children’s hospitals piloting a federated database structure using pooled data (millions of encounters) to look at obesity, hypertension and other factors.  Currently involved in a large strategic effort to combine evidence based medicine with lean concepts and clinical informatics to improve care along all the IOM domains of health care quality.

Representative Publications:

  • Del Beccaro MA, Jeffries HE, Eisenberg MA, Harry ED.  Computerized provider order entry implementation (CPOE): No association with increased mortality rates in an intensive care unit (ICU). Pediatrics 2006;118:290-295.
  • Metzger J, Welebob E, Del Beccaro M, Spurr C.  Taking the measure of inpatient EHRs. J AHIMA 2007;78:24-30.
  • Migita D, Postetter L, Hagan P, Health S, Del Beccaro MA.  Governing peripherally inserted central venous catheters by combining continuous performance improvement and computerized physician order entry.  Pediatrics 2009;123(4):1155-1161.
  • Yamamoto L, Pyles L, Del Beccaro MA, et al.  Emergency information forms (EIFs) and emergency preparedness for children with special health care needs (CSHCN). Pediatrics Vol 125 No. 4 April 2010, pp 829-837.
  • Del Beccaro MA. Villanueva R, Knudson KM, Harvey EM, Langle JM, Paul W.  Decision support alerts for medication ordering in a computerized provider order entry (CPOE) system: A systematic approach to decrease alerts.  Appl Clin Inf 2010;1 3:346-362.
  • Macy M, Hall M, Shah S, et al.  Differences in designations of observation care in US freestanding children's hospitals: are they virtual or real? J Hosp Med 2011 (in press).
  • Migita R, Del Beccaro M, Cotter D, Woodward GA. Emergency department overcrowding: developing emergency department capacity through process improvement. Clinical Pediatric Emergency Medicine 2011;12(2):141-150.
  • Stapleton FB, Del Beccaro MA, Jeffries H.  Use of continuous performance improvement (CPI) in academics: A culture change. J Pediatric 2011;159(5):705-706.

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George Demiris, PhD
Professor, Biobehavioral Nursing and Health Systems
Joint Professor, Biomedical Informatics and Medical Education

Background: MSc in Medical Informatics ( University of Heidelberg); PhD in Health Informatics ( University of Minnesota).  Dr. Demiris is the Graduate Program Director of Biomedical and Health Informatics, and the Director of Clinical Informatics and Patient Centered Technologies (CIPCT).

Research: His research focuses on the use of information technology for older adults and patients with chronic conditions, the design and evaluation of "smart homes" and telehealth applications in home care and hospice. He is also examining health informatics graduate education challenges.

Other: At the University of Washington, he has a joint appointment with the School of Nursing (Biobehavioral Nursing and Health Systems). He is the Chair of the International Medical Informatics Education Working Group on Smart Homes and Ambient Assisted Living, and the Lead Convener of the Technology and Aging Group of the Gerontological Society of America.

Representative Publications:

  • Demiris G, Thompson H, Reeder B, Wilamowska K, Zaslavsky O. Using informatics to Capture Older Adults' Wellness. International Journal of Medical Informatics (in press).
  • Demiris G, Parker Oliver D, Wittenberg-Lyles E, Washington K. Use of Videophones to Deliver a Cognitive-Behavioral Therapy to Hospie Caregivers. Journal of Telemedicine and Telecare 2011; 17:142-145.
  • Demiris G, Parker Oliver D, Washington K, Thomas Fruehling L, Haggarty-Robbins D, Coorenbos A, Wechkin H, Berry D. A Problem Solving Intervention for Hospice Caregivers: A Pilot Study. Journal of Palliative Medicine 2010; 13(8):1005-1011.
  • Demiris G, Charness N, Krupinski E, Ben-Arieh D, Washington K, Wu, J, Farberow B. The role of human factors in telehealth. Telemedicine and e-health 2010; 16(4): 446-453.
  • Demiris G, Parker Oliver D, Wittenberg-Lyles E. Assessing Caregivers for Team Interventions (ACT): A New Paradigm for Comprehensive Hospice Quality Care. American Journal of Hospice and Palliative Medicine 2009;26(2):128-134.

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Beth Devine, PharmD, MBA, PhD
Dr. Devine is Associate Professor in the Pharmaceutical Outcomes Research & Policy Program, School of Pharmacy and Adjunct Associate Professor, Division of Biomedical & Health Informatics. Dr. Devine’s research program is centered at the intersection of clinical research informatics, comparative effectiveness research, medication safety, and quality. She is the lead co-investigator for the Comparative Effectiveness Research Core of the Surgical Care and Outcomes Assessment Program Comparative Effectiveness Research Network (SCOAP-CERTN; PI: Flum) – one of two AHRQ-funded grants in the Enhanced Registries for Quality Improvement and CER portfolio. On this same grant she leads the research study that is validating the extraction of semi-automated data from disparate electronic health records across select hospitals in Washington State.

A second area of research interest is evidence synthesis, where she compares treatment alternatives to inform comparative effectiveness decision-making using indirect and mixed treatment comparison methods in a Bayesian framework. Dr. Devine received her PhD in Health Services Research from the UW Department of Health Services, her doctorate in Pharmacy from the University of the Pacific, and her MBA from the University of San Francisco. She completed a residency in clinical pharmacy practice at the VA Medical Center in Palo Alto, CA; and a post-doctoral fellowship in pharmacoeconomics and outcomes research at the UW Pharmaceutical Outcomes Program, spending one year with Roche Pharma Business, Health Economics and Strategic Pricing Group, in Palo Alto, CA. Prior to launching her research career, Dr. Devine practiced clinical pharmacy with advanced practice (prescribing) privileges, and served in administrative positions related to formulary management, medication safety and quality improvement, in both academic and community medical center settings.

She is a past recipient of an AHRQ Mentored Clinical Scientist Training Award (K-08) and served as co-investigator and project lead on an AHRQ THQIT (Transforming Healthcare Quality through Technology) implementation grant where her team studied the impact of a computerized provider order entry system in the largest independent medical group in Washington State.

Representative Publications:

  • Overby CL, Tarczy-Hornoch P, Hoath J, Smith JW, Fenstermacher D, Devine EB. An Evaluation of Functional and User Interface Requirements for Pharmacogenomic Clinical Decision Support. First IEEE Conference on Healthcare Informatics, Imaging, and Systems Biology. July 27-29, San Jose, CA (peer-reviewed manuscript)
  • *Devine EB, Patel R, Dixon D, Lawless NM, Wilson-Norton JL, Sullivan SD. Assessing physician and staff attitudes toward e-prescribing adoption in primary care: Use of a survey instrument. Inform Prim Care 2010;18(3):177-87
  • Jansen JP, Fleurence R, Devine EB, Itzler R, Barrett A, Hawkins N, Lee K, Boersma C, Cappelleri JC. Interpreting indirect treatment comparisons and network meta-analysis for health care decision-making: Report of the ISPOR Task Force on Good Research Practices – Part 1. Value in Health 2011;14:417-28
  • *Devine EB, Alfonso R, Sullivan SD. Comparative effectiveness of biologic therapies in rheumatoid arthritis: An indirect comparisons approach. Pharmacotherapy 2011;31:39–51
  • Devine EB, Payne TH, Williams EC, Sittig DF, Tarczy-Hornoch P, Martin DP, Sullivan SD. Prescriber and staff perceptions of a computerized provider order entry system in primary care: A qualitative study.BMC Medical Informatics and Decision Making 2010, 10:72

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Sherrilynne Fuller, PhD
Professor, Biomedical Informatics and Medical Education
Joint Professor, Information School
Adjunct Professor, Health Services
Fellow, American College of Medical Informatics
Senior Advisor, Dean, University Libraries University of Washington

Background:  She received her BA (Biology) and MLS (information Science) degrees from Indiana University, Bloomington, Indiana, USA and her PhD (Information Science) from the University of Southern California, Los Angeles California, USA.   Fuller served as the founding head of the Division of Biomedical and Health Informatics, School of Medicine, UW and has led several large-scale campus and regional research and development projects in the areas of biomedical and health informatics, telemedicine and information technology.    One of the first web-based medical record systems in the world (Mindscape), which still in use at UW Medical Center and Harborview Medical Center, was a product of her IAIMS (Integrated Academic Information Management System) program leadership for the UW Academic Health Sciences Center.   As Director, Health Sciences Libraries, University of Washington for over twenty years she led the development of state of art library and information systems with particular emphasis on  linking library resources to clinical information systems in the UW Medical Centers and development of knowledge mining and mapping systems.  As Co-Director, Center for Public Health Informatics Fuller has led the development of innovative computing and information systems projects to improve public health practice nationally and internationally with a particular focus on open source decision support tools and  knowledge management  systems and was a contributor to the development of EpiVue, an open source data visualization tool for public health.  

Fuller has lectured, led training programs and consulted throughout the world on the development of interoperable health information systems for low resource environments and on the creation of education and research  programs in biomedical and health informatics.  Examples of international courses and workshops she has led in recent years include:  Introduction to Public Health Informatics Principles in Health Information Systems Development Within the Vietnam Health System  (Hanoi School of Public Health, Hanoi, Vietnam);  Improving Health Outcomes through Interoperability (Ministry of Health leaders and university faculty from throughout the Mekong Basin region countries  and beyond);  Health Informatics for HIV/AIDS Data Management Fellowship Program (University of Nairobi, Kenya); Biomedical and Health Informatics Resources, Tools and Technologies (multiple courses over past ten years in collaboration with Cayetano-Heredia University, Lima, Peru).  She currently leads a UW group that is part of a larger team to contribute to Strengthening HIV Strategic Health Management Information Systems in Tanzania with particular responsibility for supporting the development of the Enterprise Architecture and e-health strategy. See web page for further information including funded research.

Representative Publications:
Peer Reviewed Articles:

  • Fuller S: From Intervention Informatics to Prevention Informatics. [Invited] Bulletin of the American Society for Information Science and Technology 2011 (in press).
  • Fuller S: Tracking the Global Express: New Tools Addressing Disease Threats Across the World. [Invited] Epidemiology 2010;21(6):1-2.
  • Corbell C, Katjitae I, Mengistu A, Kalemeera F, Sagwa E, Mairizi D, Lates J, Nwokike J, Fuller S, Stergachis S. A records linkage of electronic databases for the assessment of adverse effects of antiretroviral therapy in Namibia. Pharmacoepidemiology and Drug Safety 2011 (in press).
  • Turner K, Fuller S. Patient-Held Maternal and/or Child Health Records: Meeting the Informational Needs of Patients and Healthcare Providers in Developing Countries: Online Journal of Public Health Informatics 2011 (in press).
  • Curioso WH, Fuller S, Garcia PJ, Holmes KK, Kimball AM. Ten Years of International Collaboration in Biomedical Informatics and Beyond: The AMAUTA Program in Peru. J Am Med Inform Assoc 2010;17(4):477-480.
  • Revere D, Turner A, Madhavan A, Rambo N, Bugni PF, Kimball AM, Fuller S. Understanding the information needs of public health practitioners: a literature review to inform design of an interactive digital knowledge management system. Journal of Biomedical Informatics 2007;40(4):410-421 Special Issue on Public Health Informatics.
  • Fuller S, Revere D, Bugni P, Martin G. A knowledgebase system to enhance scientific discovery: Telemakus: Biomedical Digital Libraries 2004;1:2-15.

Books:

  • Chen HC, Fuller S, Friedman C, Hersh W (co-editors). Medical Informatics: Knowledge Management and Data Mining in Biomedicine. New York, Springer, 2005.
  • Norris TE, Fuller S, Tarczy-Hornoch P, Goldberg H (co-editors). Informatics in Primary Care. New York, Springer-Verlag, 2002.

Book Chapters:

  • Revere D, Bugni PF, Dahlstrom L, Fuller S myPublicHealth: Utilizing Knowledge Management to Improve Public Health Practice and Decision Making. In: Liebowitz J, Schieber RA, Andreadis JD. Knowledge Management in Public Health. CRC Press, 2010.
  • Revere D, Fuller S. Characterizing biomedical concept relationships: Concept relationships as a pathway for knowledge creation and discovery. In: Chen HC, Fuller SS, Friedman C, Hersh W. Medical Informatics: Knowledge Management and Data Mining in Biomedicine. New York, Springer, 2005.
  • Fuller S, Masuda D, Gorman PN, Lindberg DAB. Medical Informatics and Information Access. In: Geyman JP, Hart G, Norris T (eds). Textbook of Rural Health Care. New York, McGraw-Hill, 2001.

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Rex Gantenbein, PhD
Professor, Medical Education and Public Health, University of Wyoming
Adjunct Professor, Department of Computer Science, University of Wyoming
Affiliate Professor, Biomedical and Health Informatics, University of Washington

Background: 26 years research in reliability, security, and privacy for networked computer systems; 15 years experience in telehealth/telemedicine networks and health informatics. Education: B.S. (mathematics) Iowa State University, M.S. and Ph.D. (computer science) University of Iowa. Director, University of Wyoming Center for Rural Health Research and Education. Senior member, Association for Computing Machinery, IEEE, International Society for Computers and Their Applications; member, American Telemedicine Association, Sigma Xi/ The Scientific Research Society. Current major projects: Wyoming Network for Telehealth (WyNETTE), Wyoming Telehealth Trauma Treatment Center.

Representative Publications:

  • M. Gray, C. Hassija, R. Gantenbein, R. Wolverton, T. James, and B. Robinson, “Utilization of distal technologies to meet the needs of rural survivors of domestic violence and sexual assault,” Community Psychology: New Developments. Hauppauge, NY: Nova Science Publishers (in press).
  • S.Y. Shin, R. Gantenbein, T.-W. Kuo, and J. Hong (eds.), Reliable and Autonomous Computational Science. Basel, Switzerland: Springer Basel AG (January 2011).
  • A.W. Wallace and R.E. Gantenbein, “A Framework for Structured Search of Distributed Research Resources,” Proc. 22nd Int. Conf. on Computers and Their Applications in Industry and Engineering (CAINE) (Nov. 2009), 151-156.
  • R.E. Gantenbein, “The Cowboy State Corrals Providers into a Telehealth Network,” Behavioral Healthcare 28,4 (April 2008).
  • R.E. Gantenbein and B.J. Robinson, “Decoding CODECs,” J. Telemedicine and Telecare 14 (2008), 59-61

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John Gennari, PhD
Associate Professor, Biomedical Informatics and Medical Education

Background: PhD (Computer Science) UC-Irvine. Experience: Protege developer at Stanford Medical Informatics.

Current projects: Primary focus on semantic web, knowledge representation and ontology development.  See web pages for other interests: synthetic biology, physics-based biosimulation, health-care guidelines / protocols, and cellular signaling pathways.

Representative Publications:

  • Galdzicki M, Rodriguez C, Chandran C, Sauro HM, Gennari JH. (2001). Standard Biological Parts Knowledgebase. PLoS ONE 6(2):e17005.
  • Gennari JH, Neal ML, Galdzicki M, and Cook DL. (2010). Multiple Ontologies in Action: Composite Annotations for Biosimulation Models. Journal of Biomedical Informatics, in press.
  • Gennari JH, Neal ML, Carlson B, Cook DL. (2008). Integration of Multi-Scale Biosimulation Models Via Light-Weight Semantics. Proceedings of the Pacific Symposium on Biocomputing, pp. 414-425, 2008.
  • Weng C, McDonald DW, Sparks D, McCoy J, and Gennari JH (2007). Participatory design of a colloborative clinical trial protocol writing system. The International Journal of Medical Informatics 76(S1), 245-251.
  • Gennari JH, Musen MA, Fergerson RW, Grosso WE, Cruzbezy M, Eriksson H, Noy NF, and Tu SW (2003). The Evoluation of Protege: An Environment for Knowledge-Based Systems Development. International Journal of Human-Computer Studies, 58, 89-123.

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Kenric Hammond, MD
Clinical Associate Professor, Pyschiatry and Behavior Sciences
Adjunct Clinical Associate Professor, Biomedical Informatics and Medical Education

Background: 11 yrs clinical information systems research. Dr. Hammond is the director, VA Puget Sound Health Care System Postdoctoral Fellowship In Medical Informatics.

Research: a) impact on cost/quality/outcomes of electronic medical record systems, b) natural language analysis of patient records.

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David Heckerman, MD, PhD
Distinguished Scientist at Microsoft Research
Affiliate Professor, Biomedical Informatics and Medical Education
Background: Since 1992, he has been a Senior Researcher at Microsoft, where he has created applications including the first machine-learning spam filter, data-mining tools in SQL Server and Commerce Server, handwriting recognition in the Tablet PC, text mining software in Sharepoint Portal Server, troubleshooters in Windows, and the Answer Wizard in Office.  Most recently, he has been applying methods from statistics and machine learning to problems in health, such as the design of a vaccine for HIV.

Representative Publications: 

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Eric Horvitz, MD, PhD
Affiliate Associate Professor, Biomedical Informatics and Medical Education

Background:  I'm interested in computational foundations of intelligent sensing, reasoning, and action--with a particular focus on methods for grappling with uncertainty about environments or situations. I'm also interested in models of human cognition, and in developing computational systems that leverage insights about cognition to help people to achieve their goals. Much of my work makes use of probability and decision theory, decision analysis, and, in particular, Bayesian and decision-theoretic principles. My research spans both theoretical issues and concrete, real-world applications. I'm interested in information triage and alerting that takes human attention into consideration, spanning work on notification systems, multitasking, and psychological studies of interruption and recovery.

Other interests include principles of mixed-initiative interaction that can support fluid, efficient collaborations between people and computing systems, methods for guiding computer actions in accordance with the preferences of people, search and information retrieval, and collaboration. I've also been long interested in offline and real-time optimization of the expected value of computational systems under limited and varying resources. Areas of concentration in this realm include flexible or anytime computation, ideal metareasoning for guiding computation, compilation for reducing real-time deliberation, ongoing, continual computation, and the construction of bounded-optimal reasoning systems--systems that maximize the expected utility of the people they serve, given the expected costs of reasoning, the problems encountered over time, and assertions about a system's constitution. Research in this arena includes tackling hard reasoning problems with learning and decision making methods. I'm serving as President-Elect of the American Association for Artificial Intelligence. See the AAAI web pages for more information on research and events in the AI community.

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Ira Kalet, PhD
Professor Emeritus, Radiation Oncology
Joint Professor Emeritus, Biomedical Informatics and Medical Education
Fellow, American College of Medical Informatics
Ph.D. (theoretical physics, Princeton University)Professor, Radiation Oncology (medical physics, computing) Professor (joint), Biomedical Informatics and Medical Education Adjunct Professor, Computer Science and Engineering, Biological Structure

Research interests: Symbolic computational modeling in biomedicine, particularly in oncology (cancer biology and radiation treatment planning), also drug interactions (pharmacokinetics and pharmacodynamics)| biomedical software design and engineering. 

Representative Publications: 

  • Kalet, I.J., Giansiracusa, R., Jacky, J., and Avitan, D.  A Declarative Implementation of the   DICOM-3 Network Protocol.  Journal of Biomedical Informatics, volume 36, number 3, pp. 159--176, 2003.
  • Benson, N., Whipple, M. and Kalet, I.J. A Markov Model Approach to Predicting Regional  Tumor Spread in the Lymphatic System of the Head and Neck.  Proceedings of the American Medical Informatics Association Fall Symposium, pp. 31--35, David W. Bates, John H. Holmes and Gilad Kuperman, Eds., American Medical Informatics Association, 2006.
  • Kalet, I.J.  Principles of Biomedical Informatics.  Academic Press (Elsevier), San Diego, CA,      2008.  475 pp. (monograph)
  • Kalet, I.J., Mejino, J.L. Wang, V., Whipple, M., Brinkley, J.F. Content-Specific Auditing of a Large Scale Anatomy Ontology. Journal of Biomedical Informatics, volume 42, number 3, pp. 540--549, June, 2009.
  •  Smith, W.P., Doctor, J., Meyer, J, Kalet, I.J., and Phillips,  M.H..  A Decision Aid for IMRT Plan Selection in Prostate Cancer Based on a Prognostic Bayesian Network and Markov Model.  Artificial Intelligence in Medicine, volume 46, number 2, pp. 119--130, June, 2009

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Ann Marie Kimball, MD
Professor Emeritus, Epidemiology
Professor Emeritus, Biomedical Informatics and Medical Education

Background: epidemiology, medicine. Other: Director UW MPH Program, NIH and IOM review panel member.

Funded research: the nexus between emerging infectious diseases, international trade, and climate change with a focus on international epidemiologic applications of informatics.

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Eugene Kolker, PhD
Affiliate Associate Professor, Biomedical Informatics and Medical Education
Chief Data Officer, Seattle Children's Hospital and Head, Bioinformatics &
High-throughput Data Analysis Lab, Seattle Children's Research Institute
President and Director, the BIATECH Institute

Background: MSc in Applied Mathematics & Computer Science| Ph.D. in Structural Molecular Biology (Weizmann Institute of Science). Dr. Kolker is the President & Director of The BIATECH Institute, non-profit research organization| Editor-in-Chief of “OMICS A Journal of Integrative Biology.”

Research: bioinformatics, proteomics, genomics, molecular and systems (micro)biology, statistical and algorithmic development, data analysis, standards, and integration.

Representative Publications:

  • Keller A, Nesvizhskii AI, Kolker E, Aebersold R. Empirical statistical model to estimate the accurary of peptide identifications made by MS/MS and database search.  Analytical Chemistry 2002 Oct 15;74(20):5383-92.
  • Nesvizhskii AI, Keller A, Kolker E, Aebersold R.  A statistical model for identifying proteins by tandem mass spectrometry.  Analytical Chemistry 2003 Sept 1;75(17):4646-58.
  • Goodlett DR...Kolker E.  Differential stable isotope labeling of peptides for quantitation and de novo sequence derivation.  Rapid Commun Mass Spectrom 2001;15(14):1214-21.
  • Keller A, Purvine S, Nesvizhskii AI, Stolyar S, Goodlett DR, Kolker E.  Experimental protein mixture for validating tandem mass spectral analysis.  OMICS 2002;6(2):207-212.
  • Taylor CF...Kolker E...et al.  Promoting coherent minimum reporting guidelines for biological and biomedical investigations: the MIBBI project. Nature Biotechnology 2008 Aug;26(8):889-96.

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Bill Lober, MD
Associate Professor, Biobehavioral Nursing and Health Systems
Joint Associate Professor, Biomedical Informatics and Medical Education
Joint Associate Professor, Global Health
Adjunct Associate Professor, Health Services

Background: 10 years in computer industry. His research focuses on the development, integration, and evaluation of information systems to support individual and population health. His academic interests include informatin system-based surveillance; web-based information systems; support of population based research in public health and biomedical research; computer supported collaborative work; and privacy and security. His research employs heterogeneous data integration, web infrastructures, distributed security models, and usability assessment. Specific research includes 1) facility level systems and architecture (EMR, Lab systems, interoperability) to support health care in low and middle income countries, 2) systems and architectures to support public health information exchange, 3) architecture, algorithms, and visualization strategies for integrated surveillance, 4) population-based systems to support biomedical research in HIV/AIDS, and 5) Patient Reported Outcomes and Measures (PROs) in HIV and Oncology practice and research.

Other: Director of the UW Clinical Informatics Research Group, Director of Informatics for the International Training and Education Center for Health (I-TECH), co-Director of the UW Center for Public Health informatics. 

Representative Publications:

  • Olson DR, Paladini M, Lober WB, Buckeridge DL, Working Group ID. Applying a New Model for Sharing Population Health Data to National Syndromic Influenza Surveillance: DiSTRIBuTE Project Proof of Concept, 2006 to 2009. PLoS Curr 2011;Aug 2;3:RRN1251. PubMed PMID 21894257; PubMed Central PMCID: PMC3148528.
  • Lober WB, Flowers JL. Consumer empowerment in health care amid the internet and social media. Semin Oncol Nurs 2011;Aug 27(3):169-82. doi: 10.1016/j.soncn.2011.04.002. PubMed PMID: 21783008.
  • Reeder B, Revere D, Olson DR, Lober WB. Perceived usefulness of a distributed community-based syndromic surveillance system: a pilot qualitative evaluation study. BMC Res Notes 2011;Jun 14(4):187. PubMed PMID: 21672242; PubMed Central PMCID: PMC3146436.
  • Berry DL, Blumenstein BA, Halpenny B, Wolpin S. Fann JR, Austin-Seymour M, Bush N, Karras BT, Lober WB, McCorkle R. Enhancing patient-provider communication with the electronic self-report assessment for cancer: a randomized trial. J Clin Oncol 2011;Mar 10;29(8):1029-35. Epub 2011 Jan 31. PubMed PMID: 21282548; PubMed Central PMCID: PMC3068053.
  • Kim EH, Coumar A, Lober WB, Kim Y. Addressing mental health epidemic among university students via web-based, self-screening, and referral system: a preliminary study. IEEE Trans Inf Technol Biomed 2011;Mar 15(2):301-7. Epub 2011 Jan 20. PubMed PMID: 21257386.
  • Berry DL, Halpenny B, Wolpin S, Davison BJ, Ellis WJ, Lober WB, McReynolds J, Wulff J. Development and evaluation of the personal patient profile-prostate (P3P), a Web-based decision support system for men newly diagnosed with localized prostate cancer. J Med Internet Res 2010;Dec 17;12(4):e67. PubMed PMID: 21169159; PubMed Central PMCID: PMC3056527.
  • Lober WB, Revere D, Hills R. A Lab-EMR interoperability profile as an eHealth architecture component for resource-constrained settings. Stud Health Technol Inform 2020;160(Pt 1):257-61. PubMed PMID: 20841689.
  • Van Eaton EG, McDonough K, Lober WB, Johnson EA, Pellegrini CA, Horvath KD. Safety of using a computerized rounding and sign-out system to reduce resident duty hours. Acad Med 2010;Jul 85(7):1189-95. PubMed PMID: 20592514.
  • Wolpin S, Berry DL, Kurth A, Lober WB. Improving health literacy: a Web application for evaluating text-to-speech engines. Comput Inform Nurs 2010;Jul-Aug 28(4):198-204. PubMed PMID: 20571370.
  • Kim EH, Stolyar A, Lober WB, Herbaugh AL, Shinstrom SE, Zierler BK, Soh CB, Kim Y. Challenges to using an electronic personal health record by a low-income elderly population. J 19861298; PubMed Central PMCID: PMC2802566.

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David Masuda, MD
Lecturer, Biomedical Informatics and Medical Education, Adjunct lecturer, Health Services, School of Public Health

Background: 14 years clinical experience in diagnostic radiology, 8 years experience in clinical executive leadership, 10 years experience in clinical informatics teaching.

Current interest areas: Applied informatics educational program development with a focus on leadership in health information technology and clinical informatics.

Peer-reviewed Publications:

  • “Integrating knowledge resources at the point of care: opportunities for librarians”., Fuller SS; Ketchell DS; Tarczy-Hornoch P; D. Masuda, Bull Med Libr Assoc 1999 Oct;87(4):393-403
  • “Low-bandwidth, low-cost telemedicine consultations in rural family practice.”;  Norris TE, Hart GL, Larson EH, Tarczy-Hornoch P, Masuda DL, Fuller SS, House PJ, Dyck SM.;  J Am Board Fam Pract. 2002 Mar-Apr;15(2):123-7. J Am Board Fam Pract. 2002 Mar-Apr;15(2):123-7.
  • “Development and Evaluation of Public Health Informatics at the University of Washington”;  Karras B; O’Carrol P; Oberle M; Masuda D; Lober W; Robins L; Schaad D; Scott C; Journal of Public Health Management and Practice; Vol. 8, No.3; May 2002
  • “Teaching Technology with Technology: Learning Management Systems and Anchored Modular Inquiry in Graduate Health Administration Education”; Journal of Health Administration Education; in preparation

Other Publications:

  • “Evaluation Strategies and Findings from a Regional Integrated Telemedicine Testbed”; Fuller, S, Tarczy-Hornoch, P, Masuda, D, Cannava, T, Hard, G, Larson, E, Johnson, C, Dyck, S, Kramer, W, Norris, T. " Telemedicine & Telecommunications: Options for the New Century, Proceedings, 93-94, 2001
  • “Hospital Quality Outcomes: The results of a pilot study performed to define risk adjustment and Internet report specifications”, Meyer K; Posse C; Masuda D; AMIA 2001 Poster
  • “Using a Large Group Interactive Audience Response System to Enhance Medical Student’s Understanding of Risk Information”; Wolf FM, Masuda D, Pinsky LP; May 3; Pacific Grove, CA.; 2006. OpenURL

Books:

  • “Medical Informatics and Information Access.”, Fuller SS; Masuda D; Gorman P; Lindberg DA, Chapter 15, Textbook of Rural Medicine, Geyman J; Norris T; Hart G, Editors, McGraw-Hill, 2001
  • “Telecommunications in Primary Care”; Masuda D.; Chapter 15; Primary Care Informatics, Norris T, Editor; 2002
  • Medical Informatics for Physician Executives, ACPE, 2003
  • “Careers in Clinical Computing and Medical Informatics”; Masuda D; Chapter 15; in Practical Guide to Clinical Computing Systems: Design, Operations, and Infrastructure; Elsevier; Thomas Payne, Editor; 2008
  • “Project Management for Health Information Technology”; Coplan Sand Masuda D; McGraw-Hill; 2011

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Daniel Masys, MD
Affiliate Professor, Biomedical Informatics and Medical Education
Fellow, American College of Medical Informatics

Background:  Dr. Daniel R. Masys is Affiliate Professor, Biomedical Informatics and Medical Education.  Previously he served as Professor and Chair of the Department of Biomedical Informatics, Vanderbilt University School of Medicine.  An honors graduate of Princeton University and the Ohio State University College of Medicine, he completed postgraduate training in Internal Medicine, Hematology and Medical Oncology at the University of California, San Diego, and the Naval Regional Medical Center, San Diego.  He served as Chief of the International Cancer Research Data Bank of the National Cancer Institute, National Institutes of Health, and was also Director of the Lister Hill National Center for Biomedical Communications, which is a computer research and development division of the National Library of Medicine.  He also served as Director of Biomedical Informatics at the University of California, San Diego School of Medicine, Director of the UCSD Human Research Protections Program, and Professor of Medicine.

Dr. Masys is an elected member of the Institute of Medicine of the National Academy of Sciences.  He is a Diplomate of the American Board of Internal Medicine in Medicine, Hematology, and Medical Oncology.  He is a Fellow of the American College of Physicians, and Fellow and Past President of the American College of Medical Informatics.  

Research: Dr. Masys' research interests include development of informatics infrastructure for conducting clinical and translational research, and genome-phenome correlation using phenotype data derived from electronic medical records data.

Representative Publications:

  • Kohane IS, Masys DR, Altman RB. The incidentalome: a threat to genomic medicine. JAMA 2006 Jul 12;296(2):212-5. [PMID: 16835427]
  • Duda SN, Cushman C, Masys DR. An XML model of an enhanced data dictionary to facilitate toe exchange of pre-existing linical research data in international studies. Stud Health Technol Inform. 2007:129(Pt 1):449-53. [PMID:17911757]
  • Roden DM, Pulley JM, Basford MA, Bernard GR, Clayton EW, Balser JR, Masys DR. Development of a large scale de-identified DNA biobank to enable personalized medicine.  Clin Pharmacol Ther. 2008 Sep:84(3):362-9. Epub 2008 May 21. [PMID 18500243]
  • Ritchie MD, Denny JC, Crawford DC, Ramirez AH, Weiner JB, Pulley JM, Basford MA, Brown-Gentry K. Balser JR, Masys DR. Haines JL, Roden DM. Robust replication of genotype phenotype associations across multiple diseases in an electronic medical record. Am J Hum Genet. 2010 Apr 9:86(4):560-72. Epub 2010 Apr 1. [PMC2859132]
  • Denny JC, Ritchie MD, Basford M, Pulley J, Bastarache L, Brown-Gentry K, Wang D, Masys DR, Roden DM, Crawford DC. PheWAS: Demonstrating the feasibility of a phenome-wide scan to discover gene disease associations.  Biioinformatics. 2010 May 1:26(9):1205-10. [PMC2859132]
  • Xu H, Jiang M, Oetjens M, Bowton EA, Ramirez AH, Jeff JM, Basford MA, Pulley JM, Cowen JD, Wang X, Ritchie MD, Masys DR, Roden DM, Crawford DC, Denny JC. Facilitating pharmacogenetic studies using electronic health records and natural-language processing: a case study of warfarin. J Am Med Inform Assoc. 2011 Jul-Aug;18(4):387-91. [PMC21672908]
  • Pathk J, Wang J, Kashyap S. Basford M. Li R. Masys DR, Chute CG: Mapping clinical phenotype data elements to standardized metadata repositories and controlled terminologies: the eMERGE Network experience. J Am Med inform Assoc. 2011 July-Aug;18(4):376-96. Epub 2011 May 19. [PMC21597104]

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Peter J. Myler, PhD
B.Sc.(Hons.), and Ph.D. in Biochemistry from the University of Queensland.
Member, Seattle Biomedical Research Institute
Research Professor, Pathobiology
Affiliate Professor, Biomedical Informatics and Medical Education
Adjunct Research Professor, Global Health
25 years experience in molecular parasitology, genomics and bioinformatics.

Research interests:
1. Structural genomics (high throughput protein structure determination) of biodefense and emerging infectious disease organisms -- funding through NIAID contract
2. RNAP II-mediated transcription in Leishmania - funded, renewal pending
3. Genome-wide and bioinformatics approaches to studying differentiation between insect and mammalian lifecycle stages of Leishmania -- minimal funding
4. Drug and diagnostic development for African trypanosomes and Leishmania -- funded through collaborations
5. Annotation and curation of trypanosomatid sequence and functional genomics databases -- currently funded

Informatics projects include development of sequence, functional genomics and process management databases, analytical software tools and web-based interfaces for analysis of sequence, mRNA expression and proteomics data.

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Websites:  Seattle BioMed; School of Public Health; Global Health

William Stafford Noble, PhD
Professor, Department of Genome Sciences
Adjunct Professor, Department of Computer Science and Engineering
Adjunct Professor, Department of Biomedical Informatics and Medical Education
Adjunct Professor, Department of Medicine

Background: William Stafford Noble (formerly William Noble Grundy) received the Ph.D. in computer science and cognitive science from UC San Diego in 1998.  After a one-year postdoc with David Haussler at UC Santa Cruz, he became an Assistant Professor in the Department of Computer Science at Columbia University.  In 2002, he joined the faculty of the Department of Genome Sciences at the University of Washington.  His research group develops and applies statistical and machine learning techniques for modeling and understanding biological processes at the molecular level.  Noble is the recipient of an NSF CAREER award and is a Sloan Research Fellow.

Current research: Research in the Noble lab focuses on the development and application of maching learning and statistical methods for interpreting complex biological data sets.  The lab tends to work on research problems that involve fundamental problems in biology while also pushing the state of the art in machine learning.  Currently, the lab's research can be roughly divided into two areas.

  • Chromatin and gene regulation. We use motif-based hidden Markov models to characterize collections of transcription factor binding sites in genomic DNA.  We also develop models that predict properties of chromatin from genomic DNA.
  • Analysis of mass spectrometry data.  In collaboration with Michael MacCoss's lab, we have developed a series of machine learning and statistical methods for the analysis of shotgun proteomics data.  In this field, we continue to work on protein identification and quantification, targeted proteomics, and biomarker discovery.

Representative Publications:

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Mark Oberle, MD
Associate Dean and Professor, Health Services
Professor, Epidemiology
Adjunct Professor, Biomedical Informatics and Medical Education

Background: 32 yrs in public health informatics, practice, & epidemiology research. Associate Dean for Public Health Practice, UW. Funded research: a) distance learning applications (PI on HRSA Public Health Training Center grant), b) informatics applications in advanced public health surveillance, especially related to bioterrorism preparedness (co-PI on CDC Preparedness Center grant). Co-director UW Center for Public Health Informatics.

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Patrick O'Carroll, MD
Affiliate Professor, Epidemiology
Affiliate Professor, Health Services
Affiliate Professor, Biomedical Informatics and Medical Education
Fellow, American College of Medical Informatics

Background: 19 years medical epidemiologist, 12 years public health informatics. Dr. O'Carroll is the regional Health Administrator, USPHS Region X, US Dept of Health and Human Services. Research: public health information systems projects.

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Tom Payne, MD
Clinical Associate Professor, Medicine
Clinical Associate Professor, Health Services
Clinical Associate Professor, Biomedical Informatics and Medical Education
Fellow, American College of Medical Informatics

Background: Medicine & 24 yrs medical informatics. Dr. Payne is the Medical Director, Information Technology Services, UW Medicine. Under his leadership VA Puget Sound received a 2000 Nicholas E. Davies CPR Recognition Award of Excellence.

UW research: Use and evaluation of computer-based medical records in patient care clinical research, and quality improvement with current focus on electronic documentation, computerized practitioner order entry, and natural language processing

Representative Publications:

  • Payne TH, Detmer DE, Wyatt JC, Buchan IE.National-scale clinical information exchange in the United Kingdom: lessons for the United States.  J Am Med Inform Assoc. 2011;18(1):91-8.
  • Payne TH, Patel R, Beahan S, Zehner J. The physical attractiveness of electronic physician notes. AMIA Annu Symp Proc., 2010:622-626.
  • Payne TH. Improving clinical documentation in an EMR world. Healthcare Finance Magazine. 2010 Feb;. 70-74.
  • Payne TH, tenBroek AE, Fletcher GS, Labuguen MC.  Transition from paper to electronic  inpatient physician notes.  J Am Med Inform Assoc, 2010;17:108-111.
  • Payne TH and Ash M. Use of natural language processing to extract encoded information from notes in a commercial electronic medical record system. AMIA Annu Symp Proc., 2009:1127-1129.
  • Lin CP, Payne TH, Nichol, WP, Hoey PJ, Anderson CL, Gennari JH.  Evaluating Clinical Decision Support Systems: Monitoring CPOE Order Check Override Rates in the Department of Veterans Affairs’ Computerized Patient Record System.  J Am Med Inform Assoc. 2008 Sep-Oct;15(5):620-6.

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Wanda Pratt, PhD
Associate Professor, Information School
Joint Associate Professor, Biomedical Informatics and Medical Education
Fellow, American College of Medical Informatics

Background:  developed medical expert systems for NASA, led a team of people representing common sense knowledge for the Cyc Project Education - PhD in Medical Informatics from Stanford University, and MS in Computer Science from the University of Texas.

Research Interests:  Wanda Pratt's research is motivated by the problems patients face in finding, using, and managing information.  Her research includes studying patient's work to understand their problems, developing new types of technology to address those problems, and evaluating the technology with patients.  She is also interested in using technology to improve patient-physician communication and collaboration.

Affiliations :  UW: joint appointment in the Information School, member of DuB – an alliance of faculty and students across UW exploring human computer interaction.  External: Editorial Board of the Journal of Biomedical Informatics, member of the Biomedical Library and Informatics Review Committee of the National Library of Medicine.

Representative Publications:

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James D. Ralston, MD, MPH

Associate Scientific Investigator, Group Health Research Institute
Affiliate Assistant Professor, Health Services, University of Washington School of Public Health
Affiliate Assistant Professor, Biomedical Informatics and Medical Education, University of Washington School of Medicine
Consultative Internal Medicine, Group Health Permanente

Background:  B.A. Classics (Stanford University); M.D. (University of Washington); MPH (University of Washington)

Research:  Dr. Ralston is a Health Services and Health Informatics researcher with a focus in web-based and mobile support for patients with chronic medical conditions.  Dr. Ralston also practices Internal Medicine at Group Health Cooperative.

Representative Publications:

  • Lyles CR, Harris LT, Le T, Flowers J, Tufano J, Britt D, Hoath J, Hirsch I, Goldberg HI, Ralston JD.  Qualitative Evaluation of  Mobile Phone and Web-Based Collaborative Care Intervention for Patients with Type 2 Diabetes.  Diabetes Technol Ther 2011 May;13(5):563-569.
  • Simon GE, Ralston JD, Savarino J, Pabniak C, Wentzel C, Operskalski BH.  Randomized trial of depression follow-up care by online messaging.  J Gen Intern Med 2011 Jul;26(7):698-704 PMCID: PMC3138593.
  • Harris LT, Tufano J, Le T, Rees C, Lewis GA, Evert AB, Flowers J, Collins C, Hoath J, Hirsch IB, Goldberg HI, Ralston JD.  Designing mobile support for glycemic control.  J Biomed Inform 2010;43(5):S37-40.
  • Ralston JD, Hirsch IB, Hoath J, Mullen M, Cheadle A, Goldberg HI.  Web-based collaborative care for type 2 diabetes: a pilot randomized trial.  Diabetes Care 2009;32(2):234-239.  PMCID: PMC2628685.
  • Green BB, Cook AJ, Ralston JD, Fishman PA, Catz SL, Carlson J, Carrell D, Tyll L, Larson E, Thompson RS.  Effectiveness of home blood pressure monitoring, web communication, and pharmacist care on hypertension Control.  JAMA 2008 Jun 25;299(24):2857-2867.  PMCID: PMC2715866.
  • Ralston JD, Revere D, Robins LS, Goldberg HI.  Patient experience with a diabetes support program based on an interactive electronic medical record: qualitative study.  BMJ 2004;328(7449):1159.  PMCID: PMC411089.

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Eric Rose, MD
Clinical Assistant Professor, Biomedical Informatics and Medical Education
Clinical Assistant Professor, Family Medicine

Clinical Background: Currently employed as Directory Clinical Systems, Microsoft Health Solutions Group.  Prior to that, 5 years of product management of an ambulatory EHR system (McKesson Practice Partner) and 7 years EHR management in a multi-specialty ambulatory care network (University of Washington Physicians Network).

Research interests: Electronic Medical Record design and implementation, Evidence-Based Medicine, Terminology Systems, Automated Decision-Support

Representative Publications:

  • Leviss J., ed. H.I.T. or Miss: Lessons Learned from Health Information Technology Implementations.
    AHIMA Press: Chicago, 2010. [served as Associate Editor and Contributor]
  • Rose E. Preparing for ICD-10-CM. Journal of AHIMA, July 2009.
  • Bae S., Khouangsathiene S., Morey C., O’Connor C., Rose E., and Shakil A. Implementation of a Web-Based Incident-Reporting System at Legendary Health System. In Lorenzi NM, Ash JS, Einbinder J et al. eds. Transforming Health Care Through Information, 2nd ed. Springer: New York, 2005.

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Brian K. Ross, PhD, MD
Professor, Anesthesiology
Associate Professor, Medical Education and Bioinformatics Executive Director, Institute for Surgical and Interventional Simulation (ISIS)

Background:  Brian K. Ross, M.D., Ph.D., UW Medicine professor of anesthesiology, received his Ph.D. in physiology/pharmacology from the University of North Dakota in 1975. He completed postdoctoral research in respiratory diseases at the University of Washington in 1979, where he also received his M.D. in 1983. In 1984, he completed an internship in UW School of Medicine. In 1986, Dr. Ross completed a fellowship in Obstetrical Anesthesia from the University of California at San Francisco. In 1987, he completed a residency in anesthesiology, also at the University of Washington. 

Dr. Ross has been on the UW School of Medicine faculty since 1987. In 2003, he was appointed full professor status. Dr Ross has been involved in medical simulation at the UW since 1996, when he developed the initial curriculum for the Department of Anesthesiology. Since then, he has developed 20 courses for medical students, residents, and nurses. To promote careers in health care, he performs outreach to local high schools, conducting full-scale virtual operating room scenarios using the human patient simulator. Dr. Ross is the energy behind the advancement of medical simulation within the Department of Anesthesiology, reaching throughout the UW schools of medicine, nursing, and dentistry. He identified equipment and designed the labs that became the cornerstone of the Institute for Surgical and Interventional Simulation (ISIS). Based on his vision and expertise in medical simulation, Dr. Ross was appointed by the dean of the School of Medicine to serve as the first executive director of ISIS in November 2005.He will take ISIS into its next phase, as it expands into its new offices and labs in the UW Medical Center Surgery Pavilion, and as ISIS establishes itself as the medical simulation resource for the UW, community, industry, and the five-state WWAMI region (Washington, Wyoming, Alaska, Montana, and Idaho).

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Anthony Rossini, ScD
Affiliate Associate Professor, Biomedical Informatics and Medical Education

Background: Statistics, biostatistics, and biomedical informatics, with over 25 years experience in software and information technology systems.

Research interests:  My interests lie in the intersection of statistics and informatics, especially with respect to the commoditization of technology for data analysis. Past work has included simple parallel computing, the use of virtual reality for common statistical analyses, as well as support for projects which drive interactive data analysis modalities (http://ess.r-project.org/ | http://www.bioconductor.org/). Past statistical methodology research focused on estimation for semiparametric regression models for interval censored data and drug development program design. Current research interests focus on the design of model specification languages for statistics based on Common Lisp.

I am currently Head of Biostatistics and Bioinformatics for the Novartis Pharma AG Molecular Diagnostics business unit, based Basel, Switzerland, which does R&D and commercialization of diagnostic devices to drive personalized medicine.

My current activities range from complex statistical modelling to the design and specification of informatics technologies to support reuseable, knowledge-containing statistical and mathematical models. This latter work can be thought of as data-integration for data-analytic methods (both classes and instances) along with associated metadata.

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Doug Schaad, PhD
Professor, Biomedical Informatics and Medical Education

Research: Career trajectories in the medical profession; Health outcomes associated with new orthopaedic techniques and materials; Compassion, empathy and cynicism in the professional development of physicians; Interprofessional teams and learning outcomes; Curriculum enhancement and associated performance assessment.

Background: BS degrees in Zoology and Psychology; M.Ed in Counseling and Ph.D in Measurement and Evaluation all from the University of Washington.  Hired as a graduate research assistant in the Office of Research in Medical Education in 1974.  Continuously employed within the Department of Biomedical Informatics and Medical Education since that time.  Currently, Professor and Division Head of Medical Education and Evaluation; Chairman of the First Year Curriculum committee; Senior member of the Student Progress Committee; Member of the Council on University Relations and Member of the Faculty Senate.

Other Interests: Chairman Conservation Committee of the Washington FlyFishing Club; Advisor to Washington Department of Fish and Wildlife for Steelhead and Cutthroat Management; Owner/Operator of a vineyard in the Chehalem AVA of Oregon; Executive Director of the Whitewater Creek Conservation Association.

Representative Publications:

  • King JC, Manner PA, Stamper DL, Schaad DC, Leopold SS.  Is minimally invasive total knee arthroplasty aoosciated with lower costs than traditional TKA.  Clinical Orthopaedics and Related Research 2011;469(6):1716-20.
  • Norris TE, Schaad DC, DeWitt D, Ogur B, Hunt DD.  Longitudinal integrated clerkships for medical students: An innovation adopted by Australia, Canada, South Africa, and the United States.  Acad Med 2009;Jul 84(7):902-7.
  • King J, Stamper DL, Schaad DC, Leopold SS.  Minimally invasive total knee arthroplasty compared with traditional total knee arthoplasty.  Assessment of the learning curve and the postoperative recuperative period.  J Bone Joint Surg Am 2007;July 89(7):1497-1503.
  • Mitchell PH, Belza B, Schaad DC, Robins LS, Gianola FJ, Odegard PS, Kartin D, Ballweg RA.  Working across the boundaries of health professions disciplines in education, research and service: Lessions from the University of Washington Experience.  Acad Med 2006;Oct 81(10):891-896.
  • Mouradian WE, Reeves A, Kim S, Evans R, Schaad DC, Marshall SG, Slayton R.  An oral health curriculum for medical students at the University of Washington.  Acad Med 2005;May 80(5):434-442.

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Craig Scott, PhD
Professor, Biomedical Informatics and Medical Education
Director, UW Institute for Translational Health Sciences, Evaluation Program and the NW Consortium for Clinical Assessment

Research Interests: His interests include clinical skills development and assessment, performance-based teaching and evaluation (PBL, TBL and OSCEs), international medical education and assessment of outcomes of National Science Foundation research centers.  He recently produced and directed a video for the NSF entitled "Catalysts for Innovation" and the 3rd edition of the NSF's Compendium of Industry-Nominated Technological Breakthroughs of NSF Research Centers.

Representative Publications:

  • Finkelstein C, Lan YL, Brownstein A, Scott CS.  Anxiety/Stress Reduction in Medical Educatiion: An Intervention. Med Educ 2007;Mar 41(3):258-64.
  • Mihalynuk TV, Coombs JB, Rosenfeld ME, Scott CS, Knopp RH.  Survey correlations: Proficiency and adequacy of nutrition training of medical students.  J Am Coll Nutr 2008;Feb 27(1):59-64.
  • Li Y, Scott CS, Li L.  Chinese nursing students' HIV/AIDS knowledge, attitudes and practice intentions.  Appl Nurs Res 2008;Aug 21(3):147-52,
  • Booth-LaForce C, Scott CS, Heitkemper MM, Cornman BJ, Lan MC.  CAM Attitudes and Competencies of Nursing Students and Faculty: Results of Integrating CAM into the Nursing Curriculum.  J Prof Nsg 2010;Sept-Oct 26(5):293-300.
  • Scott CS (Ed). 2009 Compendium of Industry-Nominated Technological Breakthroughs of NSF Industry/University Cooperative Research Centers.  NSF I/UCRC Center Program.  National Science Foundation.  Arlington, Virginia, 2010.  http://faculty.washington.edu/scottcs/NSF/2009/

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Linda Shapiro, PhD
Professor, Computer Science and Engineering
Adjunct Professor, Biomedical Informatics and Medical Education
Joint: Electrical Engineering

Background: 32 yrs computer science. Funded research: a) object and pattern recognition b) medical imaging c) multimedia information retrieval for medical applications d) biomedical informatics information systems e) craniofacial image analysis

Representative Publications:

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Peter Tarczy-Hornoch, MD
Acting Chair and Professor, Biomedical Informatics and Medical Education
Professor, Pediatrics (Division of Neonatology)
Adjunct Professor, Computer Science and Engineering
Fellow, American College of Medical Informatics

Background: 30 years software development (biomedical instrumentation, bioinformatics, clinical informatics), 20 years clinical medicine (pediatrics, neonatology). 

Other: Head - Division of Biomedical and Health Informatics, Director and PI of UW NLM funded Biomedical and Health Informatics Research Training Program, Deputy Director - Biomedical and Health Informatics Graduate Program, Advisory Committee for Harvard NCBC i2b2 (Informatics for Integrating Biology and the Bedside, http://www.i2b2.org/), Advisory Committee for University of California NCBC iDASH (Integrating Data for Analysis, Anonymization and Sharing, http://idash.ucsd.edu/) Advisory Committee for University of Utah CTSA (http://www.ccts.utah.edu/), Associate Editor for Translational Bioinformatics for the Journal of Biomedical Informatics, Editorial board for the Journal of the American Medical Informatics Association (jamia.bmj.com). 

Current Research : a) Foundational and applied research in the context of biomedical informatics support for translational and clinical research as part of the Institute of Translational Health Sciences (www.iths.org), b) facilitation of biospecimen acquisition and subject recruitment as part of two Life Sciences Discovery Fund grants, c) extraction of phenotype from the electronic medical record and pharmacogenomic decision support as part of the Northwest Institute of Genetic Medicine (www.nwigm.org), d) integration of whole exome data into the electronic medical record, e) data integration and clinical data repositories as part of the UW Medicine clinical computing leadership group, f) leveraging electronic medical records for comparative effectiveness research as part of the SCOAP CERTN (www.scoap.org),  g) past research on a database of available genetic testing and on the application of genetic testing (GeneTests - http://www.genetests.org/, co-PI 1995-2004, consultant 2004-6) and general purpose data integration systems (2000-2010) (http://www.biomediator.org). Other past research descriptions available at home page.

 Representative Publications:

  • Lee ES, McDonald DW, Anderson NA, Tarczy-Hornoch P. Incorporating collaboratory concepts into informatics in support of translational interdisciplinary biomedical research. Int Jour Med Inf 2009;78:10-21.
  • Shen TH, Tarczy-Hornoch P, Detwiler LT, Cadag E, Carlson CS. Evaluatin of probabilistic and logical inference for a SNP annotation system. J Biomed Inform 2010;Jun;43(3):407-18.
  • Overby C, Tarczy-Hornoch P, Hoath J, Kalet I, Veenstra D. Feasibility of incorporating genomic knowledge into electronic medical records for pharmacogenomic clinical decision support. Accepted for AMIA Translational Bioinformatics Summit 2010, as one of best papers. BMC Bioinformatics 2010;Oct 28;11 Suppl 9:S10.
  • Cadag E, Tarczy-Hornoch P. Supporting Retrieval of Diverse Biomedical Data using Evidence-aware Queries. J Biomed Inform 2010;Dec;43(6):873-82.
  • Sarkar IN, Butte AJ, Lussier YA, Tarczy-Hornoch P, Ohno-Machado L. Translational Bioinformatics: A Macroscopic Approach to Bridge the Biological and Clinical Divide. Accepted by JAMIA April 2011. 

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Jim Tufano, PhD, MHA
Acting Assistant Professor, Biomedical Informatics and Medical Education
Associate Director, Web Outreach, UW Medicine
Research Associate, Group Health Research Institute
Dr. Tufano has a BS in Biology (Juniata College); MHA (University of Minnesota); and PhD (University of Washington)

Background: health services administration and enterprise HIT implementation (10+ years); health services and clinical informatics research (10 years)

Research interests: applied clinical informatics, ICT-mediated patient-provider and provider-provider interaction, chronic disease self-management support, comparative effectiveness research, qualitative methods.

Representative Publications:

  • Participatory (re)design of a sociotechnical healthcare delivery system: the Group Health Patient-Centered Medical Home, Tufano JT, Ralston JD, Tarczy-Hornoch P, Reid RJ. Stud Health Technol Inform. 2010;157:59-65.  PMID: 20543368 [PubMed - indexed for MEDLINE]
  • Patient-centered medical home demonstration: a prospective, quasi-experimental, before and after evaluation, Reid RJ, Fishman PA, Yu O, Ross TR, Tufano JT, Soman MP, Larson EB.  Am  J Manag Care. 2009 Sep 1;15(9):e71-87.  PMID: 19728768 [PubMed - indexed for MEDLINE]
  • Designing mobile dietary management support technologies for people with diabetes,   Arsand E, Tufano JT, Ralston JD, Hjortdahl P. J Telemed Telecare. 2008;14(7):329-32. PMID: 18852310 [PubMed - indexed for MEDLINE]
  • Providers' experience with an organizational redesign initiative to promote patient-centered access: a qualitative study, Tufano JT, Ralston JD, Martin DP.  J Gen Intern Med. 2008 Nov; 23(11):1778-83. Epub 2008 Sep 4.  PMID: 18769981 [PubMed - indexed for MEDLINE]
  • In a randomized controlled trial, patients preferred electronic data collection of breast cancer risk-factor information in a mammography setting, Aiello EJ, Taplin S, Reid R, Hobbs M, Seger D, Kamel H, Tufano J, Ballard-Barbash R. J Clin Epidemiol. 2006 Jan;59(1):77-81. Epub 2005 Oct 13. PMID: 16360564 [PubMed - indexed for MEDLINE]

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Anne Turner, MD, MLIS, MPH
Assistant Professor, Department of Health Services, School of Publich Health 
Joint Assistant Professor, Biomedical Informatics and Medical Education
Dr. Anne M. Turner, MD (Dartmouth-Brown), MPH (University of Washington) and MLIS (University of Washington).

Background:  public health informatics research (>10 years); library and information science research (>10 years); and clinical pediatrics (>20 years).

Research interests:  the use of natural language processing and machine translation to improve access to public health information; public health grey literature; public health practice information needs and workflow; use of GIS for preparedness planning and targeting interventions; evaluation of public health information systems.

Other: Faculty at the UW Northwest Center for Public Health Practice (NWCPHP -  http://www.nwcphp.org/) and the UW Center for Publish Health Informatics (CPHI - http://www.cphi.washington.edu/).

Representative Publications:

  • Turner AM, Liddy ED, Bradley J, Wheatley J. Modeling public health interventions for improved access to the public health grey literature. J Med Libr Assoc 2005;93(4):487-94.
  • Revere D, Turner AM, Madhaven AM, Rambo N, Bugni P, Kimbal A, Fuller S. Understanding the information needs of publich health professionals: A literature review to inform design of an interactive digital knowledge management system. J Biomed Inform 2007;40(4):410-421.
  • Turner AM, Stavri PZ, Revere D, Altamore R. From the Ground Up: Determining the information needs and uses of local public health nurses in Oregon. Journal of Public Health Management and Practice J Med Libr Assoc 2008;96(4):335-42.
  • Turner AM, Ramey J, Lee S. Connecting public health IT systems with enacted work: Report of an ethnographic study. AMIA Annu Symp Proc 2008;Nov 6:737-41.
  • Turner AM, Petrochilos D, Nelson DE, Allen E, Liddy ED. Access and use of the internet for health information seeking: A survey of local public health professionals in the Northwest. J Public Health Manag Pract 2009;15(1):67-69.
  • Kirchhoff K, Turner AM, Axelrod A, Saavedra F. Statistical Machine Translation of Public Health Information: A Feasibility Study. JAMIA 2011;18(4):473-478. 

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Erik G. Van Eaton, MD, FACS
Assistant Professor, Department of Surgery, Division of Harborview Trauma and Burns.
Adjunct Assistant Professor, Department of Biomedical Informatics and Medical Education, Division of Biomedical and Health Informatics.

Background: An Alaskan commercial fisherman who obtained an M.D. from the University of Washington in 2001. During residency training in General Surgery in 2002, started working on applied clinical informatics projects for inpatient care. Completed an NLM Biomedical Informatics fellowship in 2005. Began clinical practice in trauma surgery, emergency general surgery, and surgical critical care in 2009 at the University of Washington Medical Center and Harborview Medical Center.

Other: Assistant Medical Director for Surgical Critical Care, University of Washington Medical Center. Service Director of the Surgical Intensive Care Unit at the University of Washington Medical Center. Member of the American College of Surgeons Committee on Informatics. Clinical Design Strategist for TransformativeMed LLC, a medical software spin-out company that is commercializing licensed biomedical informatics technology developed at the University of Washington.

Current Research : a) Co-PI for UW-funded project to develop clinical informatics system for better capture of near misses and adverse events by clinical teams, b) Co-investigator on AHRQ-funded project to leverage electronic medical records for comparative effectiveness research as part of the SCOAP CERTN (www.scoap.org) project, c) NLM (NN/LM Regional Medical Libraries) funded project to explore mobile computing library resources for clinician teams at the bedside.

 Representative Publications:

  • Van Eaton EG, Tarpley JL, Solorzano CC, Cho CS, Weber SM, Termuhlen PM. Resident Education in 2011: Three Key Challenges on the Road Ahead. Surgery 2011;149(4):465-73. PMID:21295811.
  • Van Eaton EG, McDonough KA, Lober WB, Johnson EA, Pellegrini CA, Horvath KD. Safety of Using a Computerized Rounding and Sign-out System to Reduce Resident Workhours. Acad Med 2010;85(7):1189-95. PMID:20592514.
  • Sarkar U, Carter JT, Omachi TA, Vidyarthi AR, Cucina R, Bokser S, Van Eaton E, Blum M. SynopSIS: integrating physician sign-out with the electronic medical record. J Hosp Med 2007; 2(5):336-42. PMID:17935249
  • Williams RG, Silverman R, Schwind C, Fortune JB, Sutyak J, Horvath KD, Van Eaton EG, et al. Surgeon Information Transfer and Communication: Factors Affecting Quality and Efficiency of Inpatient Care. Ann Surg 2007; 245(2):159-169. PMID:17245166.
  • Van Eaton EG, Lober WB, Pellegrini CA, Horvath KD. User-driven design of a Computerized Rounding and Sign-out application. AMIA Annu Symp Proc. 2005:1145. PMID:16779431.
  • Van Eaton EG, Horvath KD, Lober WB, Rossini AJ, Pellegrini CA. A randomized, controlled trial evaluating the impact of a computerized rounding and sign-out system on continuity of care and resident work hours. J Am Coll Surg 2005; 200(4):538-45. PMID:15804467.

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Lucy Vanderwende, PhD
Senior Researcher, Microsoft Research
Affiliate Associate Professor, Biomedical Informatics and Medical Education

Background: Since 1992, senior researcher at Microsoft Research in Natural Language Processing group.  Contributed to the Word Grammar Checker, which has been shipping since 1997.  PhD in Computational Linguistics (Georgetown University), MSc in Theoretical Linguistics (Georgetown University), BA in English Language and Literature (University of Leiden, NL)

Research interests: I am broadly interested in knowledge acquisition from naturally occurring text.  Earlier, I worked on extracting lexico-semantic information from dictionaries, which we extended to encyclopedic text and eventually to general domain text; this project is known as MindNet.  Currently, I am interested in knowledge acquisition from biomedical text, including both clinical texts, written in the course of patient care, as well as basic research literature. For the latter, it is our goal to extract and then visualize information in such a way that scientists will be able to review existing literature more broadly than is possible today; this project spans both knowledge extraction as well as summarization.  I am currently collaborating with Meliha Yetisgen-Yildiz and others on several projects that focus on extracting medical information (e.g., phenotypes) from clinical data such as radiology reports and ICU reports, using both structured and unstructured data.

Representative Publications:

  • Meliha Yetisgen-Yildiz, Bradford Glavan, Fei Xia, Lucy Vanderwende, and Mark Wurfel, 2011. “Identifying Patients with Pneumonia from Free-Text Intensive Care Unit Reports”. In Proc. of the ICML workshop on Learning from Unstructured Clinical Text, Bellevue, WA, July 2, 2011.
  • Chris Quirk, Pallavi Choudhury, Michael Gamon and Lucy Vanderwende, 2011. "MSR-NLP Entry in BioNLP Shared Task 2011". In Proc. of the Association for Computational Linguistics BioNLP  workshop, Portland, OR.
  • Hoifung Poon and Lucy Vanderwende, 2010. "Joint Inference for Knowledge Extraction from Biomedical Literature". In Proc of the NAACL-HLT, Los Angeles, CA.
  • Aria Haghighi and Lucy Vanderwende, 2009. "Exploring Content Models for Multi-Document Summarization". in Proc. of the NAACL-HLT 2009, Boulder, CO.
  • Lucy Vanderwende, 1995. "Ambiguity in the Acquisition of Lexical Information", Microsoft Tech Report no. MSR-TR-95-18.

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Thomas Wetter, PhD
Prof. of Medical Informatics, Heidelberg University, Germany
Affiliate Professor, Biomedical Informatics and Medical Education

Background: Masters degree (diploma) in Mathematics from Aachen Technical University (Germany), working on mathematical models of the human circulation. Doctoral research in biostatistics, biomedical modeling, and clinical decision support systems. 1984 PhD from Aachen Technical University on the modal logic of clinical decision support.

Research on expert systems, natural language processing, human computer interaction, speech recognition, and software quality at the IBM Germany Scientific Center. Assignments to the several national and international projects. 1992 external "Habilitation" (postdoctoral degree) from Kaiserslautern University (Germany) on formal foundations of knowledge modeling.

Current research and teaching: Since 1997 Prof. in the School of Medicine of Heidelberg University (Germany). In charge of the medical informatics curriculum for students of medicine. Teaching in BSc and MSc curricula in a joint curriculum with Heilbronn University (Germany). IPHIE (International Partnership for Health Informatics Education) liaison for Heidelberg University.

Research interests include clinical software  (challenges under 3rd world conditions, new software design paradigms), the scientometrics and dynamics of scientific discovery, and more recently consumer health informatics and clinical decision support in fields such as breast cancer or leukemia.

Representative publications:

  • Wetter, Th; To decay is system: The challenges of keeping a health information system alive; Int. J. Med. Inform. 76 (2007) (S1), pp. 252–260
  • Weires MB, Tausch B, Haug PJ, Edwards CQ, Wetter T, Cannon-Albright LA. Familiality of Diabetes Mellitus. Exp Clin Endocrinol Diabetes 115,  634-40  (2007)
  • Ndira, SP, Rosenberger KD, Wetter Th. Assessment of data quality of and staff satisfaction with an electronic health records system in a developing country (Uganda): a qualitative and quantitative comparative study. Meth Inf Med 47(6) 489-98 (2008)
  • Chen YC, Wu JC, Chen TJ, Wetter T. A publicly available database dramatically accelerates academic production. BMJ 342 (7792) 297-98 2011. [SCI] [PMID:21285219]
  • Chen YC, Yeh HY, Wu JC, Haschler I, Chen TJ, Wetter T. Taiwan's national health insurance research database: administrative health care database as study object in bibliometrics. Scientometrics 86 365-80 (2011). [SCI][SSCI] (online DOI)

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Fred Wolf, PhD
Professor, Biomedical Informatics and Medical Education
Adjunct Professor, Health Services, Epidemiology
Fellow, American College of Medical Informatics

Background: My own research over the past 30 years has focused on the study of 1) clinical reasoning, decision making, and judgment under uncertainty, 2) dissemination and evaluation of new technology, including decision support systems, 3) evidence-based medicine, systematic reviews and meta-analysis of educational and healthcare interventions, including comparative effectiveness research and training, and 4) evaluation of clinical and translational research interventions and training. This work dates back to the mid-1980s with the publication in JAMA of my research on diagnostic reasoning and heuristics and biases, and the publication of Meta-analysis: Quantitative Methods for Research Synthesis in the Sage Series on Quantitative Applications in the Social Sciences (Vol. 59).  The JAMA article is cited in Jerome Groopman’s best-selling book on How Doctor’s Think as one of two articles to read “For those interested in the Bayesian approach” to decision making and led to my first NIH R01-supported research program, while my work in meta-analysis has led to my collaboration and co-authorship of many systematic evidence reviews as part of the International Cochrane Collaboration. Formerly, I was professor of postgraduate medicine and health professions education, and director of the Learning Resource Center and the Laboratory for Computing and Cognition (LC3), at the University of Michigan Medical School and a Visiting Scholar at the UK Cochrane Centre and Green College, University of Oxford. I currently am Co-Principal Investigator and Program Director for a new NIH Administrative Supplement for Comparative Effectiveness Research (CER) Workforce Development: The ITHS Institute for CER Training and Web-based Toolkit.

Representative Publications:

  • DeShazo JP, LaVallie DL, Wolf FM. (2009). Publication trends in the medical informatics literature: 20 Years of  "Medical Informatics" in MESH. Journal of the American Medical Informatics Association, BMC Medical Informatics and Decision Making, 2009 Jan 21;9(1):7.
  • Forsetlund L, Bjorndal A, Rashidian A, Jamtvedt G, O'Brien MA, Wolf F, Davis D, Odgaard-Jensen J, Oxman AD (2009). Continuing education meetings and workshops: effects on professional practice and health care outcomes. Cochrane Database of Systematic Reviews, 2009 Apr 15;(2):CD003030.
  • Bond GE, Burr R, Wolf FM, Feldt K (2010). The Effects of a web-based intervention on psychosocial well-being among adults age 60 and older with diabetes: A randomized trial. The Diabetes Educator, 36 (3):446-456.
  • Emerson W, Brand RA, Heckman JD, Warme WJ, Wolf FM, Leopold SS (2010). Testing for the presence of positive-outcome bias in peer review: A randomized controlled trial. Archives of Internal Medicine 170 (21):1934-1939.
  • Sprague D, LaVallie DL, Wolf FM, Jacobsen C, Sayson K, Buchwald D (2011). Influence of graphic format on comprehension of risk information among American Indians. Medical Decision Making 31(3):437-43.

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Fei Xia, PhD
Associate Professor, Linguistics Department
Adjunct Associate Professor, Biomedical Informatics and Medical Education

Background: B.S. in Computer Science (Peking University), M.S. and Ph.D. in Computer Science (University of Pennsylvania), Research Staff Member at the IBM T. J. Watson Research Center at Yorktown Heights, NY before joining UW in 2005.

Research interests: Her research area is natural language processing (NLP), and her research covers a wide range of NLP tasks including morphological analysis, grammar extraction and grammar generation, treebank development, machine translation, and creating resources for low-density languages. She is especially interested in bio-NLP -- that is, using NLP techniques to process biomedical data. She is currently collaborating with Meliha Yetisgen-Yildiz and others on several projects that focus on extracting medical information (e.g., critical results, recommendation, and phenotypes) from clinical data such as radiology reports and ICU reports.

Representative publications:

  • Cuijun Wu, Fei Xia, Louise Deleqer, and Imre Solti, 2011. “Statistical Machine Translation for Biomedical Text: Are We There Yet?” In the Proc. of the AMIA 2011 Annual Symposium, Washington DC, Oct 22-26, 2011.
  • Meliha Yetisgen-Yildiz, Martin Gunn, Fei Xia, and Tom Payne, 2011. “Automatic Identification of Critical Follow-Up Recommendation Sentences in Radiology Reports”. In the Proc. of the AMIA 2011 Annual Symposium, Washington DC, Oct 22-26, 2011.
  • Meliha Yetisgen-Yildiz, Bradford Glavan, Fei Xia, Lucy Vanderwende, and Mark Wurfel, 2011. “Identifying Patients with Pneumonia from Free-Text Intensive Care Unit Reports”. In Proc. of the ICML workshop on Learning from Unstructured Clinical Text, Bellevue, WA, July 2, 2011.
  • Scott Russell Halgrim, Fei Xia, Imre Solti, Eithon Cadag, Ozlem Uzuner, 2011. “A cascade of MaxEnt classifiers applied to extracting medication information from discharge summaries”, Journal of Biomedical Semantics 2011,  2 (Suppl 3):S2.
  • Ozlem Uzuner, Imre Solti, Fei Xia, and Eithon Cadag, 2010. “Community Annotation Experiment for Ground Truth Generation for the i2b2 Medication Challenge”,  Journal of the American Medical Informatics Association (JAMIA),  17:519-523. 

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Meliha Yetisgen-Yildiz, PhD
Assistant Professor, Biomedical Informatics and Medical Education
Adjunct Assistant Professor, Linguistics Department
Background: PhD in Information Science (University of Washington), MSc in Computer Engineering (Middle East Technical University), BSc in Computer Engineering (Bilkent University).
Research Areas: Statistical natural language processing, bio-medical text mining and information retrieval.

Representative Publications:

  • Yetisgen-Yildiz M, Glavan BJ, Xia F, Vanderwende L, Wurfel MM. Identifying patients with pneumonia from Free Text Intensive Care Unit Reports. In Proceedings of Learning from Unstructured Clinical Text Workshop of ICML '2011. Bellevue, WA, July, 2011.
  • Yetisgen-Yildiz M, Gunn ML, Xia F, Payne TH.  Automatic Identification of Critical Fellows Up Recommendation Sentences in Radiology Reports. In Proceedings of the American Medical Informatics Association Fall Symposium (AMIA'11). Washington  DC, October, 2011.
  • Luo Z, Yetisgen-Yildiz M, Weng C. Dynamic Categorizatiion of Clinical Research Eligibility Criteria by Hierarchical Clustering. Journal of Biomedical Informatics, 2011 (Accepted).
  • Yetisgen-Yildiz M, Solti I, Xia F, Halgrim SR. Preliminary experiments with Amazon's Mechanical Turk for Annotating Medical Named Entities. Proceedings of Creating Speech and Language Data with Amazon's Mechanical Turk Workshop of NAACL'2010, 2010.
  • Yetisgen-Yildiz M, Pratt W. A New Evaluation Methodology for Literature Based Discovery. Journal of Biomedical Informatics. 2009, Vol. 42, No. 4, pp 633-643.

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Brenda Zierler, PhD, RN, RVT
Professor, Biobehavioral Nursing and Health System
Associate Director, Institute for Simulation and Interprofessional Studies
Adjunct Professor, Department of Surgery, Vascular Division, School of Medicine;
Adjunct Professor, Department of Health Services, School of Public Health
Adjunct Professor, Biomedical Informatics and Medical Education

Representative Publications:

Email:  brendaz
Website